Music creation is either done in the box and you only hear the results or you record your
instruments in and in that case the signal path itself would affect sound quality.
You've picked a rather random choice of interfaces there (in regards to features
and I/O) what exactly do you need and wish to achieve in your music proudction?
I.e. are you recording a full band at the same time or an instrument at a time? Are you
only working in the box and simply need a playback solution?
More info please!
Check out our currently running, audio creation competition with a huge selection of prizes @ Scan Velocity 2014