Prior to that I was mostly trying to do it with Waves' de-hiss and de-hum tools, and RX2's de-hiss plugin gives noticeably fewer artifacts.
The de-humming plugin can sometimes make things "ring" a little (i.e. if your feed a sharp drum hit into it) - I guess that's what inevitably happens when you fire a transient at extremely sharp notch filters...
The de-clicker sometimes misbehaves with its latency compensation in my Reaper, but I raised a bug with Izotope and they did issue an update which cured this a bit.
I particularly like the spectral display where you can lasso little noises and attenuate them on their own.
With all these types of plugins, I find it often pays to not use them too aggressively in any case: your ears can get too focussed on hiss, hum and crackles, but it's seldom necessary to remove them *entirely* - just reduce them a bit so that the listener's ears can focus on the music... at this point, the human brain's own clever filtering system tends to remove the hiss all by itself.
~~~ A weasel hath not such a deal of spleen as you are tossed with! www.feline1.co.uk ~~~